Le Centre de recherche

Nos tutelles

Rechercher




Accueil du site > Emploi
/ Thèses / Stages
> Offres de thèses > 2019

Construction of dynamic multi-compartmentalized artificial cells via droplet-based microfluidics

PHD CHEMISTRY, STARTING FALL 2019, BORDEAUX, FRANCE

The design and construction of artificial cells holds great promise to fabricate functional colloidal systems for micro-reactors technology and synthetic biology. To achieve spatiotemporal control over multiple reactions, we will here exploit the synergistic interactions between capsules and coacervates droplets (produced by liquid-liquid phase separation in water) to assemble stimuli-responsive multi-compartmentalized ensembles. Microfluidic tools will be used to fabricate well-defined compartments and quantitatively study their dynamic interactions in response to various environmental cues. Chemical coupling between compartments will allow implementing higher-order collective behaviours. Overall, the expected outcome will provide new opportunities for the fabrication of complex artificial cells.

Student profile : Master of physical-chemistry

PLEASE CONTACT (CV) :
- Jean-Christophe Baret
Centre de Recherche Paul Pascal (CRPP) UMR 5031
115 Av Schweitzer, 33600 Pessac, FRANCE ;
E-mail : Jean-Christophe Baret ; Tél : 05 56 84 56 34

- Nicolas Martin
Centre de Recherche Paul Pascal (CRPP) UMR 5031
115 Av Schweitzer, 33600 Pessac, FRANCE ;
E-mail : Nicolas Martin ; Tél : 05 56 84 30 20